sc-VirusScan Overview

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The sc-VirusScan method consists of two major modules:

  • A virus screening module

  • sc-RNAseq analysis module

The results from both modules are integrated and allow detection and classification of viral pathogens in single-cell RNA datasets.

The virus screening module utilizes the Kraken2 tool for swift taxonomic classification of input sequences, enabling rapid identification and classification of viral sequences.

The sc-RNAseq analysis module processes single-cell RNA data by internally executing a sequence of steps using Cell Ranger.

The results obtained from both modules are integrated to produce a count matrix.